Staging and Follow-up of Esophageal Cancer

Variant: 1   Newly diagnosed esophageal cancer. Pretreatment clinical staging. Initial imaging.
Procedure Appropriateness Category
CT chest and abdomen with IV contrast Usually Appropriate
FDG-PET/CT skull base to mid-thigh Usually Appropriate
MRI chest and abdomen without and with IV contrast May Be Appropriate
FDG-PET/MRI skull base to mid-thigh May Be Appropriate
CT chest abdomen pelvis with IV contrast May Be Appropriate (Disagreement)
Radiography chest Usually Not Appropriate
Fluoroscopy upper GI series Usually Not Appropriate
MRI chest and abdomen without IV contrast Usually Not Appropriate
CT chest abdomen pelvis without and with IV contrast Usually Not Appropriate
CT chest abdomen pelvis without IV contrast Usually Not Appropriate
CT chest and abdomen without and with IV contrast Usually Not Appropriate
CT chest and abdomen without IV contrast Usually Not Appropriate
Variant: 2   Esophageal cancer. Imaging during treatment.
Procedure Appropriateness Category
FDG-PET/CT skull base to mid-thigh Usually Appropriate
MRI chest and abdomen without and with IV contrast May Be Appropriate
FDG-PET/MRI skull base to mid-thigh May Be Appropriate
Radiography chest Usually Not Appropriate
Fluoroscopy upper GI series Usually Not Appropriate
MRI chest and abdomen without IV contrast Usually Not Appropriate
CT chest abdomen pelvis with IV contrast Usually Not Appropriate
CT chest abdomen pelvis without and with IV contrast Usually Not Appropriate
CT chest abdomen pelvis without IV contrast Usually Not Appropriate
CT chest and abdomen with IV contrast Usually Not Appropriate
CT chest and abdomen without and with IV contrast Usually Not Appropriate
CT chest and abdomen without IV contrast Usually Not Appropriate
Variant: 3   Esophageal cancer. Posttreatment imaging. No suspected or known recurrence.
Procedure Appropriateness Category
CT chest and abdomen with IV contrast Usually Appropriate
FDG-PET/CT skull base to mid-thigh Usually Appropriate
CT chest abdomen pelvis with IV contrast May Be Appropriate
Radiography chest Usually Not Appropriate
Fluoroscopy upper GI series Usually Not Appropriate
MRI chest and abdomen without and with IV contrast Usually Not Appropriate
MRI chest and abdomen without IV contrast Usually Not Appropriate
FDG-PET/MRI skull base to mid-thigh Usually Not Appropriate
CT chest abdomen pelvis without and with IV contrast Usually Not Appropriate
CT chest abdomen pelvis without IV contrast Usually Not Appropriate
CT chest and abdomen without and with IV contrast Usually Not Appropriate
CT chest and abdomen without IV contrast Usually Not Appropriate
Variant: 4   Esophageal cancer. Posttreatment imaging. Suspected or known recurrence.
Procedure Appropriateness Category
CT chest and abdomen with IV contrast Usually Appropriate
FDG-PET/CT skull base to mid-thigh Usually Appropriate
CT chest abdomen pelvis with IV contrast May Be Appropriate (Disagreement)
Radiography chest Usually Not Appropriate
Fluoroscopy upper GI series Usually Not Appropriate
MRI chest and abdomen without and with IV contrast Usually Not Appropriate
MRI chest and abdomen without IV contrast Usually Not Appropriate
MRI head without and with IV contrast Usually Not Appropriate
MRI head without IV contrast Usually Not Appropriate
FDG-PET/MRI skull base to mid-thigh Usually Not Appropriate
CT chest abdomen pelvis without and with IV contrast Usually Not Appropriate
CT chest abdomen pelvis without IV contrast Usually Not Appropriate
CT chest and abdomen without and with IV contrast Usually Not Appropriate
CT chest and abdomen without IV contrast Usually Not Appropriate

Initial imaging is defined as imaging at the beginning of the care episode for the medical condition defined by the variant. More than one procedure can be considered usually appropriate in the initial imaging evaluation when:

  • There are procedures that are equivalent alternatives (i.e., only one procedure will be ordered to provide the clinical information to effectively manage the patient’s care)

OR

  • There are complementary procedures (i.e., more than one procedure is ordered as a set or simultaneously wherein each procedure provides unique clinical information to effectively manage the patient’s care).

The evidence table, literature search, and appendix for this topic are available at https://acsearch.acr.org/list. The appendix includes the strength of evidence assessment and the final rating round tabulations for each recommendation.

For additional information on the Appropriateness Criteria methodology and other supporting documents, please go to the ACR website at https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Appropriateness-Criteria.

Appropriateness Category Name

Appropriateness Rating

Appropriateness Category Definition

Usually Appropriate

7, 8, or 9

The imaging procedure or treatment is indicated in the specified clinical scenarios at a favorable risk-benefit ratio for patients.

May Be Appropriate

4, 5, or 6

The imaging procedure or treatment may be indicated in the specified clinical scenarios as an alternative to imaging procedures or treatments with a more favorable risk-benefit ratio, or the risk-benefit ratio for patients is equivocal.

May Be Appropriate (Disagreement)

5

The individual ratings are too dispersed from the panel median. The different label provides transparency regarding the panel’s recommendation. “May be appropriate” is the rating category and a rating of 5 is assigned.

Usually Not Appropriate

1, 2, or 3

The imaging procedure or treatment is unlikely to be indicated in the specified clinical scenarios, or the risk-benefit ratio for patients is likely to be unfavorable.













































The ACR Committee on Appropriateness Criteria and its expert panels have developed criteria for determining appropriate imaging examinations for diagnosis and treatment of specified medical condition(s). These criteria are intended to guide radiologists, radiation oncologists and referring physicians in making decisions regarding radiologic imaging and treatment. Generally, the complexity and severity of a patient’s clinical condition should dictate the selection of appropriate imaging procedures or treatments. Only those examinations generally used for evaluation of the patient’s condition are ranked.  Other imaging studies necessary to evaluate other co-existent diseases or other medical consequences of this condition are not considered in this document.  The availability of equipment or personnel may influence the selection of appropriate imaging procedures or treatments. Imaging techniques classified as investigational by the FDA have not been considered in developing these criteria; however, study of new equipment and applications should be encouraged.  The ultimate decision regarding the appropriateness of any specific radiologic examination or treatment must be made by the referring physician and radiologist in light of all the circumstances presented in an individual examination