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Nonischemic Myocardial Disease with Clinical Manifestations (Ischemic Cardiomyopathy Already Excluded)

Variant: 1   Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
Procedure Appropriateness Category Relative Radiation Level
US echocardiography transthoracic resting Usually Appropriate O
MRI heart function and morphology without and with IV contrast Usually Appropriate O
MRI heart function and morphology without IV contrast Usually Appropriate O
US echocardiography transthoracic stress May Be Appropriate O
CT heart function and morphology with IV contrast May Be Appropriate ☢☢☢☢
US echocardiography transesophageal Usually Not Appropriate O
Arteriography coronary Usually Not Appropriate ☢☢☢
Arteriography coronary with ventriculography Usually Not Appropriate ☢☢☢
MRI chest without and with IV contrast Usually Not Appropriate O
MRI chest without IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without and with IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without IV contrast Usually Not Appropriate O
MRI heart with function and vasodilator stress perfusion without and with IV contrast Usually Not Appropriate O
CT chest with IV contrast Usually Not Appropriate ☢☢☢
CT chest without and with IV contrast Usually Not Appropriate ☢☢☢
CT chest without IV contrast Usually Not Appropriate ☢☢☢
CT coronary calcium Usually Not Appropriate ☢☢☢
CTA coronary arteries with IV contrast Usually Not Appropriate ☢☢☢
FDG-PET/CT heart Usually Not Appropriate ☢☢☢☢

Variant: 2   Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
Procedure Appropriateness Category Relative Radiation Level
US echocardiography transthoracic resting Usually Appropriate O
MRI heart function and morphology without and with IV contrast Usually Appropriate O
MRI heart function and morphology without IV contrast May Be Appropriate O
CT heart function and morphology with IV contrast May Be Appropriate ☢☢☢☢
FDG-PET/CT heart May Be Appropriate ☢☢☢☢
US echocardiography transesophageal Usually Not Appropriate O
US echocardiography transthoracic stress Usually Not Appropriate O
Arteriography coronary Usually Not Appropriate ☢☢☢
Arteriography coronary with ventriculography Usually Not Appropriate ☢☢☢
MRI chest without and with IV contrast Usually Not Appropriate O
MRI chest without IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without and with IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without IV contrast Usually Not Appropriate O
MRI heart with function and vasodilator stress perfusion without and with IV contrast Usually Not Appropriate O
CT chest with IV contrast Usually Not Appropriate ☢☢☢
CT chest without and with IV contrast Usually Not Appropriate ☢☢☢
CT chest without IV contrast Usually Not Appropriate ☢☢☢
CT coronary calcium Usually Not Appropriate ☢☢☢
CTA coronary arteries with IV contrast Usually Not Appropriate ☢☢☢

Variant: 3   Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
Procedure Appropriateness Category Relative Radiation Level
US echocardiography transthoracic resting Usually Appropriate O
MRI heart function and morphology without and with IV contrast Usually Appropriate O
MRI heart function and morphology without IV contrast Usually Appropriate O
CT heart function and morphology with IV contrast May Be Appropriate ☢☢☢☢
US echocardiography transesophageal Usually Not Appropriate O
US echocardiography transthoracic stress Usually Not Appropriate O
Arteriography coronary Usually Not Appropriate ☢☢☢
Arteriography coronary with ventriculography Usually Not Appropriate ☢☢☢
MRI chest without and with IV contrast Usually Not Appropriate O
MRI chest without IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without and with IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without IV contrast Usually Not Appropriate O
MRI heart with function and vasodilator stress perfusion without and with IV contrast Usually Not Appropriate O
CT chest with IV contrast Usually Not Appropriate ☢☢☢
CT chest without and with IV contrast Usually Not Appropriate ☢☢☢
CT chest without IV contrast Usually Not Appropriate ☢☢☢
CT coronary calcium Usually Not Appropriate ☢☢☢
CTA coronary arteries with IV contrast Usually Not Appropriate ☢☢☢
FDG-PET/CT heart Usually Not Appropriate ☢☢☢☢

Variant: 4   Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
Procedure Appropriateness Category Relative Radiation Level
US echocardiography transthoracic resting Usually Appropriate O
MRI heart function and morphology without and with IV contrast Usually Appropriate O
MRI heart function and morphology without IV contrast Usually Appropriate O
CT heart function and morphology with IV contrast May Be Appropriate ☢☢☢☢
US echocardiography transesophageal Usually Not Appropriate O
US echocardiography transthoracic stress Usually Not Appropriate O
Arteriography coronary Usually Not Appropriate ☢☢☢
Arteriography coronary with ventriculography Usually Not Appropriate ☢☢☢
MRI chest without and with IV contrast Usually Not Appropriate O
MRI chest without IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without and with IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without IV contrast Usually Not Appropriate O
MRI heart with function and vasodilator stress perfusion without and with IV contrast Usually Not Appropriate O
CT chest with IV contrast Usually Not Appropriate ☢☢☢
CT chest without and with IV contrast Usually Not Appropriate ☢☢☢
CT chest without IV contrast Usually Not Appropriate ☢☢☢
CT coronary calcium Usually Not Appropriate ☢☢☢
CTA coronary arteries with IV contrast Usually Not Appropriate ☢☢☢
FDG-PET/CT heart Usually Not Appropriate ☢☢☢☢

Variant: 5   Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
Procedure Appropriateness Category Relative Radiation Level
US echocardiography transthoracic resting Usually Appropriate O
MRI heart function and morphology without and with IV contrast Usually Appropriate O
MRI heart function and morphology without IV contrast May Be Appropriate O
CT heart function and morphology with IV contrast May Be Appropriate ☢☢☢☢
FDG-PET/CT heart May Be Appropriate ☢☢☢☢
US echocardiography transesophageal Usually Not Appropriate O
US echocardiography transthoracic stress Usually Not Appropriate O
Arteriography coronary Usually Not Appropriate ☢☢☢
Arteriography coronary with ventriculography Usually Not Appropriate ☢☢☢
MRI chest without and with IV contrast Usually Not Appropriate O
MRI chest without IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without and with IV contrast Usually Not Appropriate O
MRI heart with function and inotropic stress without IV contrast Usually Not Appropriate O
MRI heart with function and vasodilator stress perfusion without and with IV contrast Usually Not Appropriate O
CT chest with IV contrast Usually Not Appropriate ☢☢☢
CT chest without and with IV contrast Usually Not Appropriate ☢☢☢
CT chest without IV contrast Usually Not Appropriate ☢☢☢
CT coronary calcium Usually Not Appropriate ☢☢☢
CTA coronary arteries with IV contrast Usually Not Appropriate ☢☢☢

Panel Members
Summary of Literature Review
Introduction/Background
Special Imaging Considerations
Initial Imaging Definition

Initial imaging is defined as imaging at the beginning of the care episode for the medical condition defined by the variant. More than one procedure can be considered usually appropriate in the initial imaging evaluation when:

  • There are procedures that are equivalent alternatives (i.e., only one procedure will be ordered to provide the clinical information to effectively manage the patient’s care)

OR

  • There are complementary procedures (i.e., more than one procedure is ordered as a set or simultaneously wherein each procedure provides unique clinical information to effectively manage the patient’s care).
Discussion of Procedures by Variant
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
A. Arteriography Coronary
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
B. Arteriography Coronary with Ventriculography
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
C. CT Chest
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
D. CT Coronary Calcium
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
E. CT Heart Function and Morphology
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
F. CTA Coronary
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
G. FDG-PET/CT Heart
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
H. MRI Chest
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
I. MRI Heart Function and Morphology
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
J. MRI Heart Inotropic Stress
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
K. MRI Heart Vasodilator Stress
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
L. Echocardiography Transesophageal
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
M. Echocardiography Transthoracic Resting
Variant 1: Suspected hypertrophic cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
N. Echocardiography Transthoracic Stress
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
A. Arteriography Coronary
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
B. Arteriography Coronary with Ventriculography
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
C. CT Chest
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
D. CT Coronary Calcium
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
E. CT Heart Function and Morphology
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
F. CTA Coronary
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
G. Nuclear Medicine
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
H. FDG-PET/CT Heart
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
I. MRI Chest
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
J. MRI Heart Function and Morphology
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
K. MRI Heart Inotropic Stress
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
L. MRI Heart Vasodilator Stress
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
M. Echocardiography Transesophageal
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
N. Echocardiography Transthoracic Resting
Variant 2: Suspected restrictive cardiomyopathy or infiltrative disease. Ischemic cardiomyopathy already excluded. Initial imaging.
O. Echocardiography Transthoracic Stress
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
A. Arteriography Coronary
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
B. Arteriography Coronary with Ventriculography
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
C. CT Chest
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
D. CT Coronary Calcium
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
E. CT Heart Function and Morphology
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
F. CTA Coronary
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
G. Nuclear Medicine
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
H. FDG-PET/CT Heart
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
I. MRI Chest
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
J. MRI Heart Function and Morphology
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
K. MRI Heart Inotropic Stress
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
L. MRI Heart Vasodilator Stress
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
M. Echocardiography Transesophageal
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
N. Echocardiography Transthoracic Resting
Variant 3: Suspected nonischemic dilated and unclassified cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
O. Echocardiography Transthoracic Stress
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
A. Arteriography Coronary
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
B. Arteriography Coronary with Ventriculography
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
C. CT Chest
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
D. CT Coronary Calcium
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
E. CT Heart Function and Morphology
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
F. CTA Coronary
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
G. FDG-PET/CT Heart
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
H. MRI Chest
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
I. MRI Heart Function and Morphology
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
J. MRI Heart Inotropic Stress
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
K. MRI Heart Vasodilator Stress
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
L. Echocardiography Transesophageal
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
M. Echocardiography Transthoracic Resting
Variant 4: Suspected arrhythmogenic cardiomyopathy (arrhythmia of ventricular origin). Ischemic cardiomyopathy already excluded. Initial imaging.
N. Echocardiography Transthoracic Stress
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
A. Arteriography Coronary
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
B. Arteriography Coronary with Ventriculography
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
C. CT Chest
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
D. CT Coronary Calcium
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
E. CT Heart Function and Morphology
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
F. CTA Coronary
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
G. FDG-PET/CT Heart
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
H. MRI Chest
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
I. MRI Heart Function and Morphology
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
J. MRI Heart Inotropic Stress
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
K. MRI Heart Vasodilator Stress
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
L. Echocardiography Transesophageal
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
M. Echocardiography Transthoracic Resting
Variant 5: Suspected inflammatory cardiomyopathy. Ischemic cardiomyopathy already excluded. Initial imaging.
N. Echocardiography Transthoracic Stress
Summary of Recommendations
Supporting Documents

The evidence table, literature search, and appendix for this topic are available at https://acsearch.acr.org/list. The appendix includes the strength of evidence assessment and the final rating round tabulations for each recommendation.

For additional information on the Appropriateness Criteria methodology and other supporting documents, please go to the ACR website at https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Appropriateness-Criteria.

Appropriateness Category Names and Definitions

Appropriateness Category Name

Appropriateness Rating

Appropriateness Category Definition

Usually Appropriate

7, 8, or 9

The imaging procedure or treatment is indicated in the specified clinical scenarios at a favorable risk-benefit ratio for patients.

May Be Appropriate

4, 5, or 6

The imaging procedure or treatment may be indicated in the specified clinical scenarios as an alternative to imaging procedures or treatments with a more favorable risk-benefit ratio, or the risk-benefit ratio for patients is equivocal.

May Be Appropriate (Disagreement)

5

The individual ratings are too dispersed from the panel median. The different label provides transparency regarding the panel’s recommendation. “May be appropriate” is the rating category and a rating of 5 is assigned.

Usually Not Appropriate

1, 2, or 3

The imaging procedure or treatment is unlikely to be indicated in the specified clinical scenarios, or the risk-benefit ratio for patients is likely to be unfavorable.

Relative Radiation Level Information

Potential adverse health effects associated with radiation exposure are an important factor to consider when selecting the appropriate imaging procedure. Because there is a wide range of radiation exposures associated with different diagnostic procedures, a relative radiation level (RRL) indication has been included for each imaging examination. The RRLs are based on effective dose, which is a radiation dose quantity that is used to estimate population total radiation risk associated with an imaging procedure. Patients in the pediatric age group are at inherently higher risk from exposure, because of both organ sensitivity and longer life expectancy (relevant to the long latency that appears to accompany radiation exposure). For these reasons, the RRL dose estimate ranges for pediatric examinations are lower as compared with those specified for adults (see Table below). Additional information regarding radiation dose assessment for imaging examinations can be found in the ACR Appropriateness Criteria® Radiation Dose Assessment Introduction document.

Relative Radiation Level Designations

Relative Radiation Level*

Adult Effective Dose Estimate Range

Pediatric Effective Dose Estimate Range

O

0 mSv

 0 mSv

<0.1 mSv

<0.03 mSv

☢☢

0.1-1 mSv

0.03-0.3 mSv

☢☢☢

1-10 mSv

0.3-3 mSv

☢☢☢☢

10-30 mSv

3-10 mSv

☢☢☢☢☢

30-100 mSv

10-30 mSv

*RRL assignments for some of the examinations cannot be made, because the actual patient doses in these procedures vary as a function of a number of factors (e.g., region of the body exposed to ionizing radiation, the imaging guidance that is used). The RRLs for these examinations are designated as “Varies.”

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Disclaimer

The ACR Committee on Appropriateness Criteria and its expert panels have developed criteria for determining appropriate imaging examinations for diagnosis and treatment of specified medical condition(s). These criteria are intended to guide radiologists, radiation oncologists and referring physicians in making decisions regarding radiologic imaging and treatment. Generally, the complexity and severity of a patient’s clinical condition should dictate the selection of appropriate imaging procedures or treatments. Only those examinations generally used for evaluation of the patient’s condition are ranked.  Other imaging studies necessary to evaluate other co-existent diseases or other medical consequences of this condition are not considered in this document. The availability of equipment or personnel may influence the selection of appropriate imaging procedures or treatments. Imaging techniques classified as investigational by the FDA have not been considered in developing these criteria; however, study of new equipment and applications should be encouraged. The ultimate decision regarding the appropriateness of any specific radiologic examination or treatment must be made by the referring physician and radiologist in light of all the circumstances presented in an individual examination.