ACR–ACNM–ARS–SNMMI PRACTICE PARAMETER FOR THE PERFORMANCE OF THERAPY WITH RADIUM-223 DICHLORIDE

PREAMBLE

I. INTRODUCTION

II. PHYSICAL PROPERTIES

III. INDICATIONS

IV. QUALIFICATIONS AND RESPONSIBILITIES OF PERSONNEL

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

1. Clinical Evaluation

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

2. Quality Management

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

3. Informed Consent

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

4. Procedure

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

5. Radiation precautions

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

6. Published Clinical Reports

V. SPECIFICATIONS OF THE EXAMINATION AND TREATMENT

A. General Procedures

7. Clinical Investigation in additional Neoplasms

VI. DOCUMENTATION

VII. ACR STATEMENT ON THERAPEUTIC USE OF UNSEALED RADIOPHARMACEUTICAL SOURCES

VIII. RADIATION SAFETY

ACKNOWLEDGEMENTS

Writing Committee – members represent their societies in the initial and final revision of this practice parameter

ACR
Akin, Esma A MD, Co-Chair
Wallner, Paul DO, Co-Chair
Morris, Zachary MD
Rabatic, Bryan MD

ACNM
Alexander, Sindu MD
Mulugeta, Philipose G MD
Saboury, Babak MD

ARS
Barry, Parul MD
Deville, Curtiland MD
Kishan, Amar MD
Sharma, Navesh DO

SNMMI
Colletti, Patrick M MD
Kuo, Phillip H MD, PhD
Pandit-Taskar, Neeta MD

Committee on Practice Parameters – Nuclear Medicine and Molecular Imaging

(ACR Committee responsible for sponsoring the draft through the process)

Ghesani, Munir V MD, Chair	Subramaniam, Rathan M MBA, MD, MPH, PhD, Chair	Aboian, Mariam MD, PhD	Akin, Esma A MD
Bartel, Twyla B DO, MBA	Dibble, Elizabeth H MD	Gerard, Perry S MD	Karagulle Kendi, A. Tuba MD
Marcus, Charles MD	Mercier, Gustavo A MD, PhD	Peacock, Justin G MD, PhD	Solnes, Lilja B MBA, MD
Surasi, Devaki Shilpa MD	Trout, Andrew T MD	Wong, Terence Z MD, PhD	Zukotynski, Katherine MD, PhD

Committee on Practice Parameters and Technical Standards

(ACR Committee responsible for sponsoring the draft through the process)

Newell, Mary S MD, Chair

Caplin, Drew M MD

Committee on Practice Parameters – Radiation Oncology

(ACR Committee responsible for sponsoring the draft through the process)

Schechter, Naomi MD, Chair	Berkowitz, Aviva MD	Chao, Samuel MD	Davis, Brian J MD, PhD
Frank, Steven J MD	Freedman, Laura MD	Garsa, Adam MD	Lo, Simon S. ChB, MB
Morris, Zachary MD	Rabatic, Bryan MD	Reilly, Michael PhD	Saeed, Hina MD
Sio, Terence Tai-Weng MD, MS	Wallner, Paul DO

Larson, David B MBA, MD, Chair, Commission on Quality and Safety

Rohren, Eric MD, PhD, Chair, Commission on Nuclear Medicine & Molecular Imaging

Small, William MD, Chair, Commission on Radiation Oncology

Comments Reconciliation Committee

Siebert, Derrick MD - CSC, Chair	Weissman, Ian DO - CSC, Co-Chair	Akin, Esma A MD	Alexander, Sindu MD
Barry, Parul MD	Bartel, Twyla B DO, MBA	Caplin, Drew M MD	Chao, Samuel MD
Colletti, Patrick M MD	Crummy, Timothy MD, MHA - CSC	Deville, Curtiland MD	Ghesani, Munir V MD
Kishan, Amar MD	Kuo, Phillip H MD, PhD	Larson, David B MBA, MD	Morris, Zachary MD
Mulugeta, Philipose G MD	Newell, Mary S MD	Pandit-Taskar, Neeta MD	Rabatic, Bryan MD
Rohren, Eric MD, PhD	Saboury, Babak MD	Schechter, Naomi MD	Schoppe, Kurt MD - CSC
Sharma, Navesh DO	Small, William MD	Subramaniam, Rathan M MBA, MD, MPH, PhD	Wallner, Paul DO

REFERENCES